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Image Search Results
Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Article Title: Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice
doi: 10.1161/JAHA.121.023131
Figure Lengend Snippet: A , Representative serial echocardiographic B‐ and M‐mode images of the LV, originating from the same animal over time. B through F , Echocardiographic assessed LV mass (LVM; B ), heart weight/tibia length (HW/TL) ratio ( C ), LV ejection fraction (EF; D ), and LV cardiac index ( E ) from C57BL/6J (BL6) and NZO cohorts. In addition, LV end‐diastolic pressure (LVEDP; F ) and LV end‐systolic pressure (LVESP; F ) were assessed by microtip catheters (presented as median±interquartile range). G , Exemplary hematoxylin and eosin (H&E)– and picrosirius (PS) red–stained cardiac cross‐sections from age‐matched cohorts. H , Cardiac regions showing cell infiltration (upper panel), fibrotic areas (middle panel), and presence of CD68 + ‐cell (lower panel). I , Quantitative analyses of cardiac cross‐sectional area and PS‐stained total collagen content in age‐matched animal cohorts. Total numbers are indicated in parentheses. Data are presented as mean±SEM. * P <0.05 vs age‐matched BL6 controls, # P <0.05 vs baseline measurement at the age of 6 weeks (wks).
Article Snippet: The external jugular vein and common carotid artery were exposed, and a
Techniques: Staining